Multimodality treatment of malignant pleural mesothelioma

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چکیده

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Multimodality therapy for malignant pleural mesothelioma.

Mesothelioma is a rare disease for which neither single modality nor bimodality therapy improves survival. For this reason, from 1980 to 1995, we used trimodality therapy in an attempt to improve survival in selected patients at Brigham and Women's Hospital and Dana-Farber Cancer Institute. One hundred twenty patients underwent trimodality treatment involving extrapleural pneumonectomy followed...

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Multimodality approach to malignant pleural mesothelioma

INTRODUCTION: We report a case of diffuse malignant pleural mesothelioma (DMPM) in a 68 years old male patient who was admitted for right sited pleural effusion. The patient was treated by multimodality approach consisting in surgical treatment with Extrapleural Pleuropneumonectomy followed by chemotherapy with Cisplatin and Pemetrexed. He had a disease free period of one year and survived for ...

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There are three major challenges in the diagnosis of malignant pleural mesothelioma: mesothelioma must be distinguished from benign mesothelial hyperplasia; malignant mesothelioma (and its subtypes) must be distinguished from metastatic carcinoma; and invasion of structures adjacent to the pleura must be demonstrated. The basis for clarifying the first two aspects is determination of a panel of...

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There are three major challenges in the diagnosis of malignant pleural mesothelioma: mesothelioma must be distinguished from benign mesothelial hyperplasia; malignant mesothelioma (and its subtypes) must be distinguished from metastatic carcinoma; and invasion of structures adjacent to the pleura must be demonstrated. The basis for clarifying the first two aspects is determination of a panel of...

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Malignant pleural mesothelioma (MPM) is the most common primary malignancy of the pleura. The occurrence of malignant mesothelioma is typically related to exposure to mineral fibers such as asbestos and erionite.[1‐3] Reports suggest that genetic factors may also play a role in MPM.[4] Moreover, latency periods that are the period of time between the first exposure to asbestos and a disease dia...

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ژورنال

عنوان ژورنال: F1000Research

سال: 2018

ISSN: 2046-1402

DOI: 10.12688/f1000research.15796.1